So close so different: what makes the difference?

What makes psoriatic and rheumatoid arthritis so different?

In many ways, it may be easier to highlight what rheumatoid arthritis (RA) and psoriatic arthritis (PsA) have in common. They are both common conditions characterised by a spectrum of features or clinical manifestations in different organ systems that have led many to conclude that they are actually 'disease syndromes'. Furthermore, many of the organ systems that are affected in both conditions...

What makes the heart rhythm so intricate?

What makes Federer look so elegant?

Everyday we come across thousands of sportsmen in action. Each of them have their own style of play and make varied impressions on the viewers. Despite this expected variability in the impression they make, there are certain inherent qualities of their play like their poise, the economy of their movement, flow of their movement etc. which make some of them more watchable to most of us. For exam...

What makes gouty inflammation so variable?

Acute gout arthritis flares contribute dominantly to gout-specific impaired health-related quality of life, representing a progressively increasing public health problem. Flares can be complex and expensive to treat, partly due to the frequent comorbidities. Unmet needs in gout management are more pressing given the markedly increasing gout flare hospital admission rates. In addition, chronic g...

What Makes Measuring Software So Hard?

41 address those needs—thereby making measurement more appealing. While the disparity discussed here involves measurement, it applies to all areas of software process improvement. For example, the Software Engineering Institute's Capability Maturity Model for Software is silent on two of the three strategies of high-performing organizations—customer intimacy and product innovation. Like traditi...